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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Prof. Scott Silverman, University of Illinois, Urbana-Champaign
DNA as a Catalyst for Bioorganic Chemistry
The Silverman laboratory studies fundamental and applied aspects of the nucleic acids, DNA and RNA. This presentation focuses on the development and application of DNA as a catalyst (deoxyribozyme). Our initial studies of DNA catalysts have focused on issues of chemical selectivity, especially regioselectivity and site-selectivity during ligation of two RNA substrates. More recently, our efforts are expanding to study deoxyribozymes that catalyze reactions of non-oligonucleotide substrates, including substrates that are small-molecule compounds and peptides, with an eye towards applications in vitro and in vivo.
For more information contact Dr. Yomi Oyelere (404-894-4047).
