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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Prof. Cornelia Bohne, University of Victoria, British Columbia
Dynamics of Small and Large Supramolecular Systems: From Cucurbit[7]uril to Serum Albumins
Organic Chemistry Seminar Series
Dynamics is an essential features of supramolecular systems that can be explored to achieve new chemical function not accessible with molecular systems. Guiding principles in the field have been to increase the complexity of various systems and to provide concepts and building blocks to achieve the bottom-up development of nanoscale systems. The development of kinetic methodology to study the fast dynamics involved in supramolecular systems will be described for host-guest complexes with increasing complexity. The host systems described are: (i) Cucurbit[n]urils, which are macrocyclic hosts that have shown much higher binding efficiencies than other macrocycles, (ii) bile salt aggregates that have two binding sites with different properties and (iii) serum albumins which have multiple binding sites and where photochirogenesis was shown to be most efficient for binding sites with moderate binding affinity.
For more information contact Prof. Laren Tolbert (404-894-4093).
