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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Dr. Rami Hannoush, Genentech, Inc.
Tools to perturb and image Wnt signaling
Joint Organic/Biochemistry Seminar Series
Our research program is centered on two themes. The first involves the development of tools for pharmacological validation of novel drug targets in cancer signaling and neurodegenerative diseases. In particular, we have been investigating protein-targeting strategies for disrupting the Wnt signaling pathway in cancer. Dissecting novel protein-protein interactions that regulate Wnt signaling enhances our understanding of the pathway at a molecular level, and enables development of targeted therapeutics against it. The second focus area in our lab is the development of chemical tools for monitoring protein posttranslational modifications in single cells. For example, we recently developed fatty acid analogues for imaging myristoylated and palmitoylated proteins. Both of these themes will be discussed during the seminar.
For more information contact Prof. Wendy Kelly (404-385-1154).
