Prof. Greg Challis, University of Warwick, UK

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Event Details
  • Date/Time:
    • Wednesday April 11, 2012 - Thursday April 12, 2012
      4:00 pm - 4:59 pm
  • Location: MoSE 3201A
  • Phone:
  • URL:
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  • Fee(s):
    N/A
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Contact

Shirley Tomes
Chemistry & Biochemistry
Contact Shirley Tomes
404-894-0591

Summaries

Summary Sentence: Prof. Greg Challis, University of Warwick, UK

Full Summary: Prof. Greg Challis, University of Warwick, UKElucidating and exploiting novel biosynthetic C-H functionalization reactionsJoint Biochemistry/Organic Divisions Seminar

Prof. Greg Challis, University of Warwick, UK

Elucidating and exploiting novel biosynthetic C-H functionalization reactions

Joint Biochemistry/Organic Divisions Seminar

The selective functionalization of C-H bonds is a “holy grail” of chemistry that is attracting considerable current interest. The biosynthetic pathways to numerous bioactive natural products involve highly selective C-H functionalization reactions that are difficult or impossible to mimic using man-made catalysts. The discovery and mechanistic investigation of novel enzymes that mediate remarkable C-H functionalization reactions in the biosynthesis of antimalarial and phytotoxic natural products will be described. Efforts to exploit these enzymes for the production of novel natural product analogues will be summarised.

For more information please contact Prof. Wendy Kelly (404-385-1154).

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School of Chemistry and Biochemistry

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Status
  • Created By: Shirley Tomes
  • Workflow Status: Published
  • Created On: Oct 19, 2011 - 8:00pm
  • Last Updated: Oct 7, 2016 - 9:50pm