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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Anthony Awojoodu - Advisor, Ed Botchwey, PhD
Mobilization and Engraftment of Long Term Hematopoietic Stem Cells with S1P Receptor Signaling
Harnessing the body’s regenerative system is dependent on the ability to control the location & activity of stem cells. Current strategies to mobilize hematopoietic stem cells are expensive, timely and often ineffective. Sphingosine 1-phosphate (S1P) is a signaling lipid active in a vast array of biological processes. We have shown that S1P receptor regulation mobilizes HSC into circulation without affecting their ability to engraft & repopulate.
Didi Eze - Advisor, Valeria Milam, PhD
Exploring Locked Nucleic Acids as a Reversible Biomaterials Assembly Tool
Oligonucleotides have potential as a programmable biomaterials assembly and disassembly tool. LNA is a promising nucleic acid analog due to its reportedly low cytotoxicity. Past work has focused on reversing DNA-linked assemblies (in the absence of cells) through thermal denaturation steps. Here, we focus on programming the assembly and disassembly of LNA-linked colloidal particles via competitive hybridization events under isothermal conditions. The Graduate and Post-Doc (GaP) Seminar Series is a weekly event of biotechnology related research presentations by two graduate students or post-docs of IBB and is co-sponsored by BME. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD.