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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Megan Richards
404-385-0783
Summary Sentence: "Controlling the Fate of Cells Post Transplantation" - Jeffrey Karp, PhD - Harvard Stem Cell Institute
Full Summary: Jeffrey Karp, PhD, will speak as a guest of the Stem Cell Engineering Center on November 8th in the Petit Institute.
Jeffrey Karp, PhD - Harvard Stem Cell InstituteJeffrey Karp, PhD - Harvard Stem Cell Institute
Controlling the Fate of Cells Post Transplantation
Control of cell fate and its extracellular environment is critical for tissue regeneration and cell therapy. This talk will explore methods to enhance the engraftment of systemically infused stem cells through engineering the surface of cells to induce a robust rolling response. This approach is based on leukocytes ability to target tissues via specific interactions with the vascular endothelium. In addition, a novel strategy to engineer cells with an intracellular depot of phenotype altering agent's will be described that can be used for programming cell fate via both intracrine-, paracrine-, and endocrine-like mechanisms. The talk will also examine the potential of cell surface sensors that can be used to detect signals within the cellular nano-environment with unprecedented spatial and temporal resolution and should be useful for elucidating niche biology in vivo.
Every semester, the SCEC welcomes a keynote speaker to the Georgia Tech stem cell research community to speak on behalf of their university, institution, industry, or research lab in regards to stem cell engineering. This experience is meant to broaden the stem cell research alliance between local researchers and worldwide experts for the purposes of communicating stem cell advancements across the globe while developing future collaborative opportunities.
