Closing the Loop to Target Brain Glioblastomas

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Contact

Joshua Stewart

College of Engineering

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Summaries

Summary Sentence:

Algorithm-controlled focused ultrasound system uses microbubbles to open a pathway for a powerful immunotherapy to reach brain tumors

Full Summary:

Algorithm-controlled focused ultrasound system uses microbubbles to open a pathway for a powerful immunotherapy to reach brain tumors.

Media
  • Closed-Loop Controlled Focused Ultrasound for Immunotherapy Closed-Loop Controlled Focused Ultrasound for Immunotherapy
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“Closing the loop” has become one of the jargony cliches of the business world. But in the world of cancer immunotherapy, closing the loop could be an innovation that unlocks powerful therapies for hard-to-treat brain cancers called glioblastomas.

Researchers at Georgia Tech and Emory University have developed a system that uses ultrasound-induced microbubbles to help a powerful immunotherapy target brain tumors and a custom algorithm to continuously fine tune the bubbles for maximum impact.

Their closed-loop controlled focused ultrasound system proved effective in boosting survival rates in mouse models, including eradicating the entire tumor in at least one case. They described their approach Nov. 18 in the journal Science Advances.

Read the full story on the College of Engineering website.

Additional Information

Groups

College of Engineering, Research Horizons

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Keywords
Costas Arvanitis, Brain Cancer, Glioblastoma, focused ultrasound, immunotherapy, blood-brain barrier, go-bio, go-researchnews
Status
  • Created By: Joshua Stewart
  • Workflow Status: Published
  • Created On: Nov 18, 2022 - 3:12pm
  • Last Updated: Nov 18, 2022 - 3:12pm