Frontiers Seminar: Peter Kasson (University of Virginia)

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Event Details
  • Date/Time:
    • Monday November 14, 2022
      3:30 pm - 4:30 pm
  • Location: MoSE 3201A
  • Phone:
  • URL:
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact

Hosted by: M. G. Finn

Summaries

Summary Sentence: Frontiers Seminar

Full Summary: No summary paragraph submitted.

Title:
Viral entry and its discontents: measuring dynamics, inhibitors, and anticipating viral evolution
 
 
Abstract:
Enveloped viruses infect human cells using surface proteins that bind cellular receptors and drive membrane rearrangements to permit genome entry.  We develop computational and experimental methods to understand this dynamic process, permit assessment of therapeutic candidates, and understand the barriers to host-species jumps.  I will discuss two core technologies and our work, both past and future, to apply them:  1) computational methods to drive model refinement using sparse experimental data and 2) a platform that uses programmable DNA assembly to chemically bypass the requirement for viruses to bind human receptors.  We can use this platform to measure how and where antibodies and small molecules inhibit viral entry but also go one step beyond to anticipate future pandemic threats and how they may be combatted.

Additional Information

In Campus Calendar
No
Groups

School of Chemistry and Biochemistry

Invited Audience
Faculty/Staff, Public, Undergraduate students
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Status
  • Created By: Michele Yager
  • Workflow Status: Published
  • Created On: Oct 13, 2022 - 4:38pm
  • Last Updated: Nov 2, 2022 - 6:36am