Researchers Describe First Functioning "Lipidome" of Mouse Macrophage

*********************************
There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
*********************************

Contact
School of Biology
Biology
Contact School of Biology
404-894-3700
Sidebar Content
No sidebar content submitted.
Summaries

Summary Sentence:

Researchers Describe First Functioning "Lipidome" of Mouse Macrophage

Full Summary:

For the first time, scientists have described not only the identities and quantities of fat species in a living mammalian cell - in this case, a mouse macrophage or white blood cell - but they also report how these lipids react and change over time to a bacterial stimulus triggering the cell’s immune response.

For the first time, scientists have described not only the identities and quantities of fat species in a living mammalian cell - in this case, a mouse macrophage or white blood cell - but they also report how these lipids react and change over time to a bacterial stimulus triggering the cell's immune response.

Writing in the December 17 issue of the /Journal of Biological Chemistry/, lead author Edward A. Dennis, PhD, distinguished professor of pharmacology, chemistry and biochemistry at the University of California San Diego School of Medicine, said the work culminates more than seven years of effort by scientists in LIPID MAPS, a national consortium of 12 research laboratories at nine "core" universities, medical research institutes and life sciences companies collaborating to study the structure and function of lipids. The laboratory of Dr. Al Merrill (School of Biology, Georgia Tech) was responsible for the sphingolipid analyses and characterization carried out by the consortium.

Read Full Article

Additional Information

Groups

Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

Categories
Institute and Campus, Chemistry and Chemical Engineering, Student and Faculty, Engineering, Life Sciences and Biology, Nanotechnology and Nanoscience, Research, Physics and Physical Sciences
Related Core Research Areas
No core research areas were selected.
Newsroom Topics
No newsroom topics were selected.
Keywords
Al Merrill, Biology, Georgia Tech, IBB
Status
  • Created By: Floyd Wood
  • Workflow Status: Published
  • Created On: Jan 2, 2011 - 8:00pm
  • Last Updated: Oct 7, 2016 - 11:08pm