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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Spatiotemporal dynamics of phage-biofilm interactions by Hemaa Selvakumar (Curtis-Weitz Lab)
Bacteriophage (‘phage’) - viruses that infect and lyse bacteria - can be deployed therapeutically to treat infections caused by bacterial pathogens. However most reported studies of the therapeutic potential of phage neglect the spatial heterogeneity in bacterial communities, e.g., in microcolonies and biofilms. We investigate the spatiotemporal dynamics arising from interactions between P. aeruginosa and phage. Time-dependent high resolution confocal imaging is used to examine how phage propagate through spatial domains of bacteria and the resulting density-dependent structures that emerge.
