Metabolic Rules of Microbial Community Assembly

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Event Details
  • Date/Time:
    • Thursday February 20, 2020
      10:55 am
  • Location: Room 1117-1118, Marcus Nanotechnology Building, 345 Ferst Dr. NW, Atlanta, GA 30332
  • Phone:
  • URL:
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact
No contact information submitted.
Summaries

Summary Sentence: A Biological Sciences Seminar by Alvaro Sanchez, Ph.D.

Full Summary: No summary paragraph submitted.

Media
  • Alvaro Sanchez Alvaro Sanchez
    (image/jpeg)
Alvaro Sanchez, Ph.D.
Department of Ecology & Evolutionary Biology
Yale University
 
ABSTRACT
Microbes form complex multi-species communities that play important roles across the biosphere. Metabolism is a major determinant of microbial community assembly, but a quantitative and predictive connection between nutrient composition and microbiome composition (and function) is lacking. Can we possibly predict which communities will form in a given, known environment?  We have addressed this question through a combination of metabolic modeling and quantitative experiments. Experimentally, we have followed a high-throughput "enrichment-culture" approach to cultivate large numbers of natural communities in synthetic environments with a defined nutrient composition. Our experiments indicate that community assembly in replicate environments follows simple and reproducible quantitative metabolic rules, despite substantial species-level variability. Explicit, quantitative metabolic models allow us to predict the assembly of communities in novel nutrients, suggesting that the relationship between nutrient composition and microbiome assembly can be explained from first principles.
 
Host: William Ratcliff, Ph.D.

Additional Information

In Campus Calendar
Yes
Groups

School of Biological Sciences

Invited Audience
Faculty/Staff, Postdoc, Public, Graduate students, Undergraduate students
Categories
Seminar/Lecture/Colloquium
Keywords
School of Biological Sciences Seminar, Alvaro Sanchez, William Ratcliff
Status
  • Created By: Jasmine Martin
  • Workflow Status: Published
  • Created On: Jan 17, 2020 - 4:32pm
  • Last Updated: Jan 17, 2020 - 4:37pm