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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Jenny Jiang, PhD
Associate Professor
Biomedical Engineering
The University of Texas at Austin
ABSTRACT
Various T cells based cancer immunotherapies have been quite effective in treating several types of cancers. However, to further improve the efficacy of T cell based cancer immunotherapy or make it available to other types of cancers requires us to have a comprehensive understanding of the complex T cells repertoire and their interaction with cancer. In the past several years, we have developed three tools to profile the T cell repertoire from T cell receptor diversity to T cell receptor affinity to high-throughput linking antigen specificity to single T cell receptor sequences in large scale. In this talk, I will first introduce these tool and then give examples on how we use them to answer some of the fundamental questions in systems immunology, which in turn help us design new approaches in immune engineering.
Host: Melissa Kemp, PhD
