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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Colly Mitchell - Events Manager
Summary Sentence: "Emergence of Genetic Complexity in Clonal Populations Evolving in the Lab: Implications for Cancer and Chronic Infectious Disease" - Frank Rosenzweig, Ph.D. - Georgia Tech
Full Summary: No summary paragraph submitted.
Petit Institute Breakfast Club Seminar Series"Emergence of Genetic Complexity in Clonal Populations Evolving in the Lab: Implications for Cancer and Chronic Infectious Disease"
Frank Rosenzweig Ph.D.
Professor
School of Biological Sciences
Georgia Tech
A bacterial population that initially consists of a single clone can evolve into a population teeming with many, whether or not the surrounding environment is structured, and whether or not resource levels are constant or fluctuating. Emergence of genetic complexity, measured as functional information, has been variously attributed to balancing selection, clonal interference and/or clonal reinforcement arising from either antagonistic or synergistic interactions among evolving lineages. Using a combination of theory and experiment, we seek to define the boundary conditions under which one causal mechanism prevails over another. These investigations illuminate the process of adaptive evolution in other populations that originate as a single clone: those that give rise to cancer and those that bring about chronic infectious disease.
