*********************************
There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
*********************************
"Neural Crest Migration and Possible Implications in Cancer Metastasis"
Shuyi Nie, Ph.D.
Assistant Professor
School of Biological Sciences
Georgia Tech
The neural crest is a unique population of cells in vertebrate. Induced at the neural plate border, neural crest cells detach from the neuroepithelium and migrate extensively to different parts of the embryo and give rise to multiple tissue and organs including neurons and glia, bones and cartilage, and pigment cells. Both the behavior of neural crest cells and signaling molecules in neural crest development are similar to that of metastatic cancer. In fact, dysregulation of neural crest development results in multiple cancer, including neuroblastoma, glioblastoma, and melanoma. Through studying the molecular and cellular mechanisms of neural crest cell EMT and migration, we hope to gain insights into cancer metastasis.
Georgia Tech has been a leader in the development of collaborative approaches to both cancer diagnostics and therapeutics. The mission of the Integrated Cancer Research Center (ICRC) is to facilitate integration of the diversity of technological, computational, scientific and medical expertise at Georgia Tech and partner institutions in a coordinated effort to develop improved cancer diagnostics and therapeutics.