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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Summary Sentence: BME Speaker Seminar with Brooks Lindsey, Ph.D.*
Full Summary: No summary paragraph submitted.
Brooks Lindsey, Ph.D.NIH Ruth L. Kirschstein NRSA
Postdoctoral Fellow
UNC-NCSU Joint Department of Biomedical Engineering
ABSTRACT
Cancer and cardiovascular disease are two major sources of morbidity, mortality, and healthcare costs in developed nations, accounting for 46% of all deaths in the U.S. in 2013. While many existing imaging techniques are effective for locating lesions, most lack the functional information necessary to characterize the degree of disease progression or to distinguish between adjacent diseased and healthy tissues. Recent developments in contrast agent-specific ultrasound imaging enable evaluation of tumor progression on the basis of microvascular structure at spatial resolutions of ~100 μm. We have also recently developed a new high resolution ultrasound molecular imaging technique and have demonstrated the ability to quantify spatial relationships between vascular remodeling and endothelial cell markers at these scales. Quantifying vessel tortuosity, endothelial cell marker expression, and microvascular blood flow dynamics provides complimentary physiological indicators of disease for monitoring tumor angiogenesis, guiding biopsies, or characterizing atherosclerotic plaques at earlier stages than current technology. The underlying physics and instrumentation requirements for acquiring these images will be discussed along with opportunities for employing these techniques. Finally, the importance of comprehensive design of all aspects of an imaging system—including transducers, processing algorithms, contrast agents, and image analysis—in enabling functional imaging capabilities (i.e. morphological, molecular, hemodynamic) will be examined.
Host: Stanislav Emelianov, Ph.D.
Thursday, January 12
10:30 a.m.
Georgia Tech: Whitaker Bldg, McIntire Room 3115
Videoconference:
Emory: HSRB E182
Georgia Tech: TEP 104
