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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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"Bioprocessing Strategies for Cell and Gene Therapy Products"
Ivan Wall, Ph.D.
Senior Lecturer
Biochemical Engineering
University College London
Cell and gene therapy has enormous promise to meet a healthcare treatment void. However, there are still many manufacturing challenges to overcome to achieve commercial viability. Our group’s research sits at the interface of biology and bioprocessing for cell & gene therapy. We seek to address challenges that relate to process development and product characterization by ensuring that processes and analytics are appropriate to the sensitive cell material being generated. To ensure the best chance of success both in clinic and commercially, it is necessary to 1) create robust processes that do not alter the product attributes, 2) be certain that the right product measurements, linked to expected physiologic response, are being made. An overview of how we are approaching these two challenges will be presented with specific examples covering our approach to MSCs, exosomes and T-cells.
