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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Frequent failure of antibiotic treatment is becoming a serious threat to public health. Various studies of human patients or simple model systems of infection show that antibiotic treatments still fail even when infection-causing bacteria are not resistant to the antibiotics used. In this talk, I will present our recent experimental data revealing that antibiotics induce stochastic fluctuations in bacterial populations and the fluctuations lead to inconsistent treatment outcomes. Then, I will discuss a therapeutic strategy to exploit the fluctuations to facilitate treatment success.