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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Summary Sentence: BME Chair Candidate, Susan Margulies: Research Seminar,
Full Summary: No summary paragraph submitted.
Susan Margulies, Ph.D.
The overall goal of my research program is to determine the mechanical thresholds associated with functional and structural injury in the brain and lung, ultimately to open avenues for injury prevention, intervention and treatment. Our lab pioneered functional and structural injury threshold measurement in the brain and lung to identify mechanisms of traumatic brain and lung injury. The research thrusts are united by a common, integrated approach consisting of experiments to measure cell or tissue function/structure under carefully controlled loading conditions (deformations or forces), complemented by computational models that extend these microscopic findings to a broad range of real-world, macroscopic environments. By integrating across scale and species and across computational and experimental approaches in our novel interdisciplinary platform, we translate basic research to clinical injury prevention and treatment strategies.
In traumatic brain injury (TBI), we integrate animal experiments, tissue and surrogate tests, clinical studies, and computational models to define biomechanical and molecular cascades, assess outcomes, and develop TBI interventions and treatments for children. By increasing our understanding of how head injuries occur in children, this crucial information enables engineers to design safer protective equipment (e.g. car seats, helmets) for children and provides physicians with tools to assist them in the diagnosis and treatment of head injuries in children.
