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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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A platelet interacts with the injured vascular surface at the beginning of blood clotting. The platelet uses a glycoprotein molecule to bind von Willebrand factor (VWF) to resist the dislodging force from the bloodstream. The force unfolds the domain of the molecule that binds VWF, which prolongs binding and promotes unfolding of the domain of the molecule that is close to the platelet membrane. These cooperative unfolding events lead to strong calcium signaling inside the platelet. (Credit: Yunfeng Chen, Georgia Tech)
