Sam Brown, Georgia Insitiute of Technology

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Event Details
  • Date/Time:
    • Thursday September 8, 2016 - Friday September 9, 2016
      11:00 am - 10:59 am
  • Location: Georgia Tech, EBB 1005
  • Phone: (404) 894-3700
  • URL:
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact

If you have questions about logistics or would like to set up an appointment with the speaker, please contact the School of Biology's administrative office at bio-admin@biology.gatech.edu.

Summaries

Summary Sentence: Sam Brown, Georgia Insitiute of Technology

Full Summary: In my job talk a year ago I asked ‘can we make evolution-proof drugs?’, and offered theory and experimental evidence that this is possible. I showed that by targeting bacterial collective traits (eg. extracellular digestion) we can make drugs that select against resistance mutations. In this talk I will pick up on the problem I spelt out at the end of my job talk - our candidate ‘evolution proof’ treatments are sadly not the most effective drugs - and outline solutions that aim to restore and maintain the efficacy of our most potent drugs, our fading arsenal of old antibiotics. I will outline three overlapping strategies that we are currently developing - defusing resistance with adjuvants, killing resistant cells with phages and conditioning treatment choices on rapid and specific resistance diagnoses. In principle, these strategies offer a route to effective and evolutionarily robust treatments. 

Back to the Future: Making Old Antibiotics Work Again

Additional Information

In Campus Calendar
No
Groups

School of Biological Sciences

Invited Audience
Undergraduate students, Faculty/Staff, Graduate students
Categories
Seminar/Lecture/Colloquium
Keywords
Sam Brown, School of Biological Sciences Seminar, School of Biology
Status
  • Created By: Jasmine Martin
  • Workflow Status: Published
  • Created On: Aug 3, 2016 - 8:59am
  • Last Updated: Apr 13, 2017 - 5:15pm