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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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CSE/Seminar Announcement
By: Eberhard O. Voit
Integrative BioSystems Institute
Department of Biomedical Engineering, Georgia Institute of Technology
Date: Friday, February 13, 2009
Time: 2:00pm-3:00pm
Location: Klaus 2447
For more information please contact Dr. Richard Fujimoto; fujimoto@cc.gatech.edu
Title:
Translation of Biological Systems into Computable Models
Abstract:
The grand challenge of computational systems biology is the translation of biological systems into mathematical structures that permit computational analysis, interrogation, and simulation. This translation process requires two major steps, which however are not independent of each other. One is the construction of a suitable mathematical model representation and the second is the determination of parameter values that match the model to experimental data, thereby making it realistic. This presentation will discuss challenges, as well as partial solutions, for both steps. At the core of the discussion will be a suitable default approach for initiating both steps, namely a “canonical” modeling framework called Biochemical Systems Theory. The adjective “canonical” refers to the pre-described mathematical structures of models within this framework, which offer valuable guidance for model construction and analysis. While focusing primarily on issues of model design and parameter estimation, I will also demonstrate the methods with actual applications to biological data.
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You are cordially invited to attend a reception that will follow the seminar to chat informally with faculty and students. Refreshments will be provided.
To receive future announcements, please sign up to the cse-seminar email list:
https://mailman.cc.gatech.edu/mailman/listinfo/cse-seminar
Hope to see you there!
