Matthias Fischer, Max Planck Heidelberg

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Event Details
  • Date/Time:
    • Friday October 9, 2015 - Saturday October 10, 2015
      11:00 am - 10:59 am
  • Location: Georgia Tech, EBB 1005
  • Phone: (404) 894-3700
  • URL:
  • Email: bio-admin@biology.gatech.edu
  • Fee(s):
    N/A
  • Extras:
Contact

If you have questions about logistics or would like to set up an appointment with the speaker, please contact the School of Biology's administrative office at bio-admin@biology.gatech.edu.

Summaries

Summary Sentence: Matthias Fischer, Max Planck Heidelberg

Full Summary: Abstract:Virophages are double-stranded DNA viruses with 20-30 kilobase pair (kbp) long genomes that replicate inside single-celled eukaryotes such as amoebae and flagellates. Their propagation depends on a co-infecting giant DNA virus of the family Mimiviridae, because virophages replicate within the cytoplasmic virion factory of the giant DNA virus. Virophages act as parasites of giant viruses and increase the survival rates of their host cells in the presence of giant viruses. In this talk, I will show that the mavirus virophage is able to integrate its genome into the nuclear genome of its host, the marine flagellate Cafeteria roenbergensis. Integrated provirophages are then reactivated and produce infectious virions in response to infection by the giant virus CroV. Virophages thus protect their hosts from lytic giant viruses, while integration into the host genome enables the virophage to persist for prolonged periods of time.

Viruses of viruses: the mutualistic relationship between virophages and their protist hosts

Additional Information

In Campus Calendar
No
Groups

School of Biological Sciences

Invited Audience
Undergraduate students, Faculty/Staff, Public, Graduate students
Categories
Seminar/Lecture/Colloquium
Keywords
Joshua Weitz, Matthias Fischer, School of Biology Seminar
Status
  • Created By: Jasmine Martin
  • Workflow Status: Published
  • Created On: Sep 17, 2015 - 12:38pm
  • Last Updated: Apr 13, 2017 - 5:18pm