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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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SAPH-ire analyzes existing data repositories of protein modifications and 3D protein structures to help scientists identify and target research on “hotspots” likely to be important for biological function. Shown is the structural projection of PTM hotspots onto the 3D structure of a heterotrimeric G protein. Regions of the protein that are modified are color coded to indicate observation frequency. SAPH-ire integrates these and other features to predict which modifications are most likely to impact the function of the protein. (Credit: Torres Laboratory)