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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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"Mass Transfer Regulation of Blood Clot Growth and Stability"
Keith Neeves, PhD
Associate Professor
Department of Chemical and Biological Engineering
Colorado School of Mines
Department of Pediatrics, University of Colorado, Denver
The formation of a clot is an exquisitely regulated biological process in which a complex
fluid, blood, undergoes a rapid transformation into a densely packed porous medium at
the site of a vascular injury. In this talk Keith Neeves will review the biophysical mechanisms that regulate the formation of a blood clot, with a focus on mass transfer limitations of platelet
agonists and inhibitors, coagulation and fibrin formation. Measurements made in
microfluidic models of vascular injury reveal that these mass transfer limitation have
important implications in the pathophysiology of bleeding and thrombotic disorders.
