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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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"Engineering the Form and Function of Virus-Like Particles"
M.G. Finn, PhD
Professor, School of Chemistry & Biochemistry
Georgia Tech
Viruses and virus-like particles are the largest scaffolds conveniently available to the molecular scientist with structures known to atomic resolution. They therefore represent unique tools with which to explore a variety of questions in nanoscience, biology, and materials research. Our work in recent years has focused on the particle derived from the bacteriophage Q-beta capsid as a model system. Methods for the chemical and genetic modification of the coat protein, its targeting to particular cell types, and its use in immunology and as a container for functional biological molecules will be described.