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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Summary Sentence: Hyewon Lee and Catera Wilder presenting
Full Summary: The Graduate and Post-Doc (GaP) Seminar Series is a weekly event of research presentations by two graduate students or post-docs conducting bio-related research. The series is organized and sponsored by the Parker H. Petit Institute for Bioengineering and Bioscience (IBB) with additional support from the Wallace H. Coulter Department of Biomedical Engineering. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD.
GaP Seminar SeriesHyewon Lee - Advisor, Hang Lu, PhD
"High-density multi-channel device for parallel stimulation and long-term monitoring cellular features in C. elegant"
Here, we developed a densely-packed multi-channel device to enable simultaneous stimulation, long-term continuous feeding, and ease repetitive imaging over 100 C. elegans. We verified the usability of the device for the high-throughput ablation with KillerRed- encoded worms. We expected that our device will greatly facilitate a broad range of developmental and functional studies in neuroscience.
Catera Wilder - Advisor, Manu Platt, PhD
"Paracring signaling of invasive breast cancer cells reduce mesenchymal stem cell differentiation and survival"
Bone metastases from breast cancer patients tend to form osteolytic lesions. Previous work has focused on how osteoclast bone resorption has contributed to the formation of the lesions, but little work has examined the affect of breast cancer cells on osteoblast. This work investigates how breast cancer cells down-regulate osteogenic differentiation and increase apoptosis to promote osteolytic lesion formation.
