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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Summary Sentence: Phil Keegan and Jenna Wilson presenting
Full Summary: The Graduate and Post-Doc (GaP) Seminar Series is a weekly event of research presentations by two graduate students or post-docs conducting bio-related research. The series is organized and sponsored by the Parker H. Petit Institute for Bioengineering and Bioscience (IBB) with additional support from the Wallace H. Coulter Department of Biomedical Engineering. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD.
GaP Seminar Series
Phil Keegan
Jenna WilsonPhil Keegan - Advisor, Manu Platt, PhD
"Role of Shear Stress on Endothelial Cell Regulation of Elastases and Collagenases under the Unique Inflammatory Conditions of Sickle Cell Disease"
Remodeling of cerebral arteries in children as early as 3 years old with sickle cell disease results in a 220-fold increase in stroke risk; however, the underlying mechanisms have not been elucidated. Here, we investigate how the pathological hemodynamic and inflammatory environment unique to sickle cell disease activates cathepsins, powerful proteases involved in arterial remodeling, in order to identify novel therapeutic targets.
Jenna Wilson - Advisor, Todd McDevitt, PhD
"A Microfluidic Tool for Single-cell Analysis of Embryoid Body Heterogeneity"
Embryonic stem cells are often cultured as embryoid bodies (EBs), a platform which allows for spontaneous differentiation and results in phenotypic heterogeneity. To explore and assess this heterogeneity, a microfluidic-based analytical method will be described which determines the characteristics of individual cells that make up a single EB.
