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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Prof. Craig Townsend, Johns Hopkins University
Recent Studies in Polyketide Natural Product Biosynthesis and Engineering
School Colloquium
If you were to ask an organic chemist “What is the most useful functional group for synthesis?” he or she is likely to answer “the carbonyl.” Only a handful of biosynthetic pathways are known, but they create the vast panoply of natural products. The synthetic versatility of the carbonyl group is evident in several of these, but one in particular—the polyketide family. How the intrinsic reactivity of this functional group is used and controlled by the giant enzymes that synthesize them will be considered, and recent discoveries about how they can be re-engineered to make new products will be illustrated.
For more information contact Prof. Wendy Kelly (404-385-1154).
