*********************************
There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
*********************************
Summary Sentence: Christopher Phaneuf and Adam Prasanphanich presenting
Full Summary: The Graduate and Post-Doc (GaP) Seminar Series is a weekly event of research presentations by two graduate students or post-docs conducting bio-related research. The series is organized and sponsored by the Parker H. Petit Institute for Bioengineering and Bioscience (IBB) with additional support from the Wallace H. Coulter Department of Biomedical Engineering. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD.
GaP Seminar Series
Christopher Phaneuf
Adam PrasanphanichChristopher Phaneuf - Advisor, Craig Forest, PhD
"An Instrument for Multi-temperature, Multi-chamber, Micro-liter Amplification of Viral DNA/RNA"
The inability of current diagnostic tools to rapidly and efficiently identify viral pathogens results in significant medical expenditures including empiric antibiotic administration and hospital admissions. We are developing an instrument that will facilitate timely, low-cost identification of viral DNA/RNA with fast thermocycling of 1 µL sample volumes within a microfluidic chip with independent thermal control of the reaction chambers.
Adam Prasanphanich - Advisor, Melissa Kemp, PhD
"Antioxidant Attenuation of TGFβ-Induced Smad Transcriptional Activity"
Elevated reactive oxygen species (ROS) and aberrant transforming growth factor beta (TGFβ) signaling are potent drivers of carcinogenesis and fibrogenesis. Antioxidants have been shown to reduce TGFβ-mediated gene expression. Our investigation has identified phosphorylation of Smad transcription factors as a redox regulated processes that may sensitize TGFβ signaling pathways in the presence of elevated ROS.
