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There is now a CONTENT FREEZE for Mercury while we switch to a new platform. It began on Friday, March 10 at 6pm and will end on Wednesday, March 15 at noon. No new content can be created during this time, but all material in the system as of the beginning of the freeze will be migrated to the new platform, including users and groups. Functionally the new site is identical to the old one. webteam@gatech.edu
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Atlanta, GA | Posted: October 12, 2009
Professor Greg Gibson is a coauthor on a review article entitled "Finding the missing heritability of complex diseases" that appeared in the 8 October issue of the journal Nature. The first paragraph of the article is below, as is a link to the full article by Manolio et al. (subscription required):
First paragraph: Genome-wide association studies have identified hundreds of genetic variants associated with complex human diseases and traits, and have provided valuable insights into their genetic architecture. Most variants identified so far confer relatively small increments in risk, and explain only a small proportion of familial clustering, leading many to question how the remaining, 'missing' heritability can be explained. Here we examine potential sources of missing heritability and propose research strategies, including and extending beyond current genome-wide association approaches, to illuminate the genetics of complex diseases and enhance its potential to enable effective disease prevention or treatment.
Full article:
http://www.nature.com/nature/journal/v461/n7265/abs/nature08494.html?lang=en
